Dr. Meghan Rice, PhD, Postdoctoral Fellow in Stoyanova Lab awarded Department of Defense, Prostate Cancer Research Program, Early Investigator Research Award for her project title:
“Defining the Role and Therapeutic Potential of Notch Signaling in Aggressive Prostate Cancer”
The overall goal of this proposal is to understand the mechanisms causing aggressive prostate cancer. The proposed project will investigate the role of Notch signaling pathway in prostate cancer to understand the mechanism through which Notch can drive the aggressive disease and determine the requirement of Notch for tumor maintenance. Additionally, we will test new treatment strategies involving two types of Notch inhibitors alone, and in combination with current standard of care treatments for castration resistant disease. This study will facilitate our understanding of fundamental molecular mechanisms underlying the development of aggressive prostate cancer and direct novel strategies regarding new combination therapies for the advanced disease.
Congratulations Dr. Rice!